3-Iodo-2-propynyl N-Butylcarbamat (IPBC)
3-Iodo-2-propynyl N-Butylcarbamat (IPBC)
3-Iodo-2-propynyl N-Butylcarbamate (IPBC)
CAS-Nr.:
55406-53-6
COA & MSDS:
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Produktdetails
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Wesentliche Details
Versand:快递, 空运, 陆运, 海运
Produkteinführung
Parameter CategoryParameter NameEnglish Value/Specification
Basic IdentificationChemical Name3-Iodo-2-propynyl butylcarbamate; Iodopropynyl butylcarbamate
Abbreviation/INCI NameIPBC; IPBC (INCI); 3-Iodo-2-propynyl N-butylcarbamate
CAS Registry Number55406-53-6
EINECS/EC Number259-627-5
Molecular FormulaC₈H₁₂INO₂
Molecular Weight281.09 g/mol
Chemical ClassIodinated propargyl carbamate; antifungal preservative; wood preservative
Physicochemical PropertiesAppearanceWhite to pale yellow crystalline powder; faint characteristic odor
Melting Point64–68 °C (literature value)
Boiling PointDecomposes prior to reaching boiling temperature (decomposes at >100 °C, releasing iodine)
Density (20 °C)1.56 g/cm³ (estimated, crystalline form)
Water Solubility (25 °C)Poorly soluble (~0.1 g/100 mL); solubility increases in alkaline aqueous systems
Organic Solvent SolubilitySoluble in ethanol, propylene glycol, acetone, toluene, and mineral oil; miscible with most cosmetic/industrial organic solvents
pH Value (1% Organic Solution)Neutral (pH 6.5–7.5)
LogP (Octanol-Water Partition Coefficient)3.5–3.8 (moderate lipophilicity, favorable for surface penetration)
StabilityStable at pH 3.0–9.0 (optimal range for cosmetics); sensitive to strong UV light (degrades, turns yellow/brown); stable under cool/dry conditions
Biological ActivityAntimicrobial SpectrumFungicidal/moldicidal (high efficacy against Aspergillus, Penicillium, Candida spp.); limited activity against bacteria (synergy needed for broad-spectrum coverage)
Mechanism of ActionInhibits fungal cell wall synthesis (targets β-1,3-glucan synthase) and disrupts mitochondrial respiration; iodide moiety enhances antifungal potency
Minimum Inhibitory Concentration (MIC)Aspergillus niger: 0.1–0.5 ppm; Penicillium chrysogenum: 0.05–0.2 ppm; Candida albicans: 0.2–0.8 ppm
Effective Concentration Range0.01–0.1% (cosmetic/personal care); 0.05–0.2% (industrial coatings); 0.1–0.5% (wood preservation)
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