Essential details
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Product Introduction
| Parameter Category | Parameter Name | English Value/Specification |
|---|---|---|
| Basic Identification | Chemical Name | 2-Phenoxyethanol; Ethylene glycol monophenyl ether; Phenoxyaethanol |
| Abbreviation/INCI Name | Phenoxyethanol; PE; 2-Phenoxyethanol (INCI) | |
| CAS Registry Number | 122-99-6 | |
| EINECS/EC Number | 204-589-7 | |
| Molecular Formula | C₈H₁₀O₂ | |
| Molecular Weight | 138.16 g/mol | |
| Chemical Class | Aromatic ether alcohol; non-formaldehyde-releasing preservative; cosmetic antimicrobial agent | |
| Physicochemical Properties | Appearance | Clear, colorless to pale yellow viscous liquid; faint floral/aromatic odor |
| Melting Point | -13 °C (literature value; liquid at room temperature) | |
| Boiling Point | 245–247 °C (lit.); decomposes slightly above boiling point | |
| Density (20 °C) | 1.105–1.110 g/cm³ | |
| Water Solubility (25 °C) | Soluble (~25 g/100 mL); miscible with water in all proportions at temperatures >40 °C | |
| Organic Solvent Solubility | Fully miscible with ethanol, propylene glycol, glycerin, acetone, and most cosmetic organic solvents; insoluble in aliphatic hydrocarbons | |
| pH Value (5% Aqueous Solution) | 6.0–7.5 (neutral to weakly acidic) | |
| LogP (Octanol-Water Partition Coefficient) | 1.3–1.5 (moderate hydrophilicity, favorable for aqueous formulations) | |
| Stability | Stable under normal storage/formulation conditions (pH 3.0–10.0); resistant to UV light; non-hygroscopic | |
| Biological Activity | Antimicrobial Spectrum | Broad-spectrum (effective against Gram-negative bacteria, Gram-positive bacteria, and some fungi/yeasts; weak activity against molds) |
| Mechanism of Action | Disrupts microbial cell membrane integrity (targets lipid bilayers) and inhibits cellular respiration; acts as a bacteriostatic/bactericidal agent at different concentrations | |
| Minimum Inhibitory Concentration (MIC) | Escherichia coli: 0.2–0.5% (v/v); Staphylococcus aureus: 0.3–0.6% (v/v); Candida albicans: 1.0–1.5% (v/v) | |
| Effective Concentration Range | 0.4–1.0% (cosmetic/personal care products); 0.5–2.0% (pharmaceutical topical formulations); 0.2–0.8% (industrial aqueous formulations) |
