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Введение в продукт
| Parameter Category | Parameter Name | English Value/Specification |
|---|---|---|
| Basic Identification | Chemical Name | 3-Iodo-2-propynyl butylcarbamate; Iodopropynyl butylcarbamate |
| Abbreviation/INCI Name | IPBC; IPBC (INCI); 3-Iodo-2-propynyl N-butylcarbamate | |
| CAS Registry Number | 55406-53-6 | |
| EINECS/EC Number | 259-627-5 | |
| Molecular Formula | C₈H₁₂INO₂ | |
| Molecular Weight | 281.09 g/mol | |
| Chemical Class | Iodinated propargyl carbamate; antifungal preservative; wood preservative | |
| Physicochemical Properties | Appearance | White to pale yellow crystalline powder; faint characteristic odor |
| Melting Point | 64–68 °C (literature value) | |
| Boiling Point | Decomposes prior to reaching boiling temperature (decomposes at >100 °C, releasing iodine) | |
| Density (20 °C) | 1.56 g/cm³ (estimated, crystalline form) | |
| Water Solubility (25 °C) | Poorly soluble (~0.1 g/100 mL); solubility increases in alkaline aqueous systems | |
| Organic Solvent Solubility | Soluble in ethanol, propylene glycol, acetone, toluene, and mineral oil; miscible with most cosmetic/industrial organic solvents | |
| pH Value (1% Organic Solution) | Neutral (pH 6.5–7.5) | |
| LogP (Octanol-Water Partition Coefficient) | 3.5–3.8 (moderate lipophilicity, favorable for surface penetration) | |
| Stability | Stable at pH 3.0–9.0 (optimal range for cosmetics); sensitive to strong UV light (degrades, turns yellow/brown); stable under cool/dry conditions | |
| Biological Activity | Antimicrobial Spectrum | Fungicidal/moldicidal (high efficacy against Aspergillus, Penicillium, Candida spp.); limited activity against bacteria (synergy needed for broad-spectrum coverage) |
| Mechanism of Action | Inhibits fungal cell wall synthesis (targets β-1,3-glucan synthase) and disrupts mitochondrial respiration; iodide moiety enhances antifungal potency | |
| Minimum Inhibitory Concentration (MIC) | Aspergillus niger: 0.1–0.5 ppm; Penicillium chrysogenum: 0.05–0.2 ppm; Candida albicans: 0.2–0.8 ppm | |
| Effective Concentration Range | 0.01–0.1% (cosmetic/personal care); 0.05–0.2% (industrial coatings); 0.1–0.5% (wood preservation) |
